Saints vs. Cowboys odds, spread: Thursday Night Football picks, top predictions by NFL model on 131-94 roll

Two teams coming off Thanksgiving Day losses will meet on Thursday Night Football as the Saints (5-6) host the Cowboys (7-4). Dallas has lost three of four and is dealing with injuries and absences, including head coach Mike McCarthy (COVID-19), who will not be in attendance. New Orleans has lost four straight, and another defeat would be the Saints’ longest ever losing streak under Sean Payton. Various key players who missed last Thursday’s games are hoping to return, including Amari Cooper and CeeDee Lamb for Dallas, as well as Mark Ingram for New Orleans.

Kickoff from Caesars Superdome is set for 8:20 p.m. ET. Dallas is favored by six points in the latest Saints vs. Cowboys odds from Caesars Sportsbook, while the Over-Under is 46. Before you lock in any Cowboys vs. Saints picks, be sure to check out the NFL predictions and betting advice from the SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up almost $7,100 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 13 of the 2021 season on an incredible 131-94 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up. 

Now, the model has simulated Cowboys vs. Saints 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and betting lines for Cowboys vs. Saints:

Saints vs. Cowboys spread: Dallas -6Saints vs. Cowboys over-under: 46 points Saints vs. Cowboys money line: Dallas -250, Saints +205DAL: Cowboys have covered six straight games against NFC opponentsNO: Under is 9-1-1 in Saints’ last 11 Thursday…..

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