Saints vs. Cowboys odds, spread: Thursday Night Football picks, predictions from NFL model on 131-94 roll

The Dallas Cowboys (7-4) will travel to the Caesars Superdome for a matchup against the New Orleans Saints (5-6) on Thursday Night Football. Sean Payton and the Saints need a victory to help them stay afloat in a tight NFC playoff race. Dallas leads the NFC East and is currently the fourth seed in the conference, so a win would continue to propel them forward in the NFL playoff picture.

Kickoff from Caesars Superdome is set for 8:20 p.m. ET. Dallas is favored by six points in the latest Saints vs. Cowboys odds from Caesars Sportsbook, while the Over-Under is 46. Before you lock in any Cowboys vs. Saints picks, be sure to check out the NFL predictions and betting advice from the SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up almost $7,100 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 13 of the 2021 season on an incredible 131-94 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up. 

Now, the model has simulated Cowboys vs. Saints 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and betting lines for Cowboys vs. Saints:

Saints vs. Cowboys spread: Dallas -6Saints vs. Cowboys over-under: 46 points Saints vs. Cowboys money line: Dallas -250, Saints +205DAL: Cowboys have covered six straight games against NFC opponentsNO: Under is 9-1-1 in Saints’ last 11 Thursday games

Featured Game | New Orleans Saints vs. Dallas Cowboys


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