NFL odds, lines, picks, spreads, bets, top predictions for Week 10, 2021: Model high on Bills, Broncos

After covering their first seven games against the spread in 2021, the Cowboys had their first major misfire last Sunday when they were blown out as double-digit favorites against the Broncos. The final score was 30-16, but Dallas scored all 16 of its points in the final 4:08 and the Broncos were in control the whole way. The Cowboys will take on the Falcons this week, and the latest Week 10 NFL odds at Caesars Sportsbook list them as nine-point favorites. Can you trust Dallas to cover one of the largest NFL spreads of the week? All of the Week 10 NFL lines are listed below, and SportsLine’s advanced computer model has all the NFL betting advice and predictions you need to make the best Week 10 NFL picks now.

The model, which simulates every NFL game 10,000 times, is up almost $7,600 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 10 of the 2021 season on an incredible 128-88 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 10 NFL odds and locked in picks for every NFL matchup. Head here to see every pick.

Top Week 10 NFL predictions

One of the model’s strongest Week 10 NFL picks is that the Bills (-12) cover the spread against the Jets. Like the Cowboys, the Bills were also a massive disappointment in Week 9, as they suffered a 9-6 loss as 14.5-point favorites over the Jaguars. Unlike Dallas, we’ve seen enough success from Buffalo in the last two-plus seasons to say that last week was likely an outlier.

Buffalo still has the No. 1 scoring defense (14.8 points per game) and ranks fourth in scoring offense (29.4). The Jets have…


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