The divisional round features the debut of each No. 1 seed in the NFL playoff bracket, as the Green Bay Packers and Tennessee Titans will take the field for the first time in the 2022 NFL playoffs. They’re the two largest favorites of the weekend, as the Packers are -5.5 against the San Francisco 49ers, while the Titans are -3.5 against the Cincinnati Bengals in the latest NFL odds at Caesars Sportsbook. Elsewhere, the Tampa Bay Buccaneers are -2.5 against the Los Angeles Rams and the Kansas City Chiefs are -2 against the Buffalo Bills.

Should bettors side with the favorites or NFL underdogs? When making the right divisional round NFL bets, a proven model can come in handy. All of the divisional round NFL lines are listed below and SportsLine’s advanced computer model has all the NFL betting advice and predictions you need to make the best divisional round NFL picks now.

The model, which simulates every NFL game 10,000 times, is up over $7,500 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters the divisional round of the 2021 NFL playoffs on an incredible 137-97 run on top-rated NFL picks that dates back to the 2017 season. Amazingly, it hasn’t missed a top-rated pick since Week 14 of the regular season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest divisional round 2022 NFL odds and locked in picks for every NFL matchup. Head here to see every pick.

Top divisional round NFL predictions

One of the model’s strongest divisional round picks is that the Buffalo Bills (+2) cover the spread against the Chiefs. Buffalo and Kansas City are both coming off resounding victories, and each has Super Bowl dreams.

While the…

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