Cardinals vs. Rams odds, spread, line: Monday Night Football picks, prediction from NFL model on 132-94 run

The Los Angeles Rams snapped a three-game losing streak with a dominant win over the Jacksonville Jaguars in Week 13 and will face their division’s top team on Monday Night Football. They’ll visit the Arizona Cardinals at State Farm Stadium to close out Week 14. The Cardinals have rattled off two consecutive double-digit wins, and Kyler Murray’s return makes them a threat to run away with the NFC West title. The Rams will be without cornerback Jalen Ramsey and tight end Tyler Higbee, who were placed on the COVID-19/reserve list.

Kickoff is slated for 8:15 p.m. ET. Arizona is favored by three points in the latest Cardinals vs. Rams odds from Caesars Sportsbook, while the Over-Under is 51. Before locking in your Rams vs. Cardinals picks, make sure to check out the NFL predictions and betting advice from the SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up almost $7,200 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 14 of the 2021 season on an incredible 132-94 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated Rams vs. Cardinals 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model’s picks. Now, here are several NFL odds and betting lines for Rams vs. Cardinals:

Cardinals vs. Rams spread: Cardinals -3Cardinals vs. Rams over-under: 51Cardinals vs. Rams money line: Cardinals -160, Rams +140 LAR: Rams are 5-0 against the spread in their last five road games against the Cardinals ARI: Cardinals are 8-2 ATS in their last 10 games

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