NFL odds, lines, picks, spreads, best bets, predictions for Week 15, 2021: Model loving Saints, Steelers

Buffalo has gone from the top of the AFC East to barely hanging on to a playoff spot following losses in four of its last six games. The Bills are currently the No. 7 seed in the AFC playoff picture, but they only have one game remaining against a team with a winning record. They will be trying to snap a two-game losing skid when they host Carolina on Sunday during the Week 15 NFL schedule. The Bills are 12-point favorites in the latest Week 15 NFL odds at Caesars Sportsbook.

Bettors have not shied away from backing Buffalo so far this week, moving the Bills from -9.5 to -12 in the NFL spreads. Should you put your money on them as well? All of the Week 15 NFL lines are listed below, and SportsLine’s advanced computer model has all the NFL betting advice and predictions you need to make the best Week 15 NFL picks now.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 15 of the 2021 season on an incredible 132-96 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 15 NFL odds and locked in picks for every NFL matchup. Head here to see every pick.

Top Week 15 NFL predictions

One of the model’s strongest Week 15 NFL picks is that the Saints (+11.5) cover the spread against the Buccaneers. The Saints snapped a five-game losing streak with a 30-9 blowout win over the Jets last week. Running back Alvin Kamara returned from a four-game absence, rushing for 120 yards and a touchdown. He also caught four passes for 25 yards, providing a much-needed spark to a struggling…

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