Cowboys vs. Eagles odds, spread, line: 2022 NFL picks, Week 18 prediction, best bets from model on 135-96 run

Playoff-bound teams will try to enter the postseason on a positive note when the Dallas Cowboys and Philadelphia Eagles collide in the teams’ regular season finale on Saturday night at Lincoln Financial Field in Philadelphia. The Cowboys (11-5) are coming off a 25-22 loss to Arizona at home, which ended the team’s four-game winning streak. Dallas, which already has clinched the NFC East title, will be either the No. 2, No. 3 or No. 4 seeds in the NFC playoffs. Meanwhile the Eagles (9-7) enter the regular season finale on a four-game winning streak and will be either the No. 6 or No. 7 seed. 

Kickoff is set for 8:15 p.m. ET. Caesars Sportsbook lists Dallas as the 3.5-point favorite in the latest Cowboys vs. Eagles odds. The over-under for total points is set at 45, up four points from the opening line. Before finalizing any Eagles vs. Cowboys picks, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model. 

The model, which simulates every NFL game 10,000 times, is up more than $7,200 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 18 of the 2021 season on an incredible 135-96 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has zeroed in on Cowboys vs. Eagles and locked in another confident against-the-spread pick. You can see the pick only at SportsLine. Now, here are several NFL betting lines and trends for Eagles vs. Cowboys:

Cowboys vs. Eagles spread: Dallas -3.5Cowboys vs. Eagles over-under: 45 points Cowboys vs. Eagles money line: Dallas -190, Philadelphia +160DAL: 12-4 against the spread this seasonPHI: Eagles lead the…..

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