One of the most anticipated matchups of the regular season takes place on Thursday Night Football. Patrick Mahomes and the Kansas City Chiefs (9-4) will visit Justin Herbert and the Los Angeles Chargers (8-5) to open Week 15. Both teams were victorious in Week 14 while fighting for playoff positioning. The Chiefs beat the Las Vegas Raiders 48-9, while the Chargers defeated the New York Giants 37-21. 

Kickoff from SoFi Stadium is set for 8:20 p.m. ET. Kansas City is favored by three points in the latest Chiefs vs. Chargers odds from Caesars Sportsbook, while the Over-Under is 52. Before locking in any Chargers vs. Chiefs picks, be sure to check out the NFL predictions and betting advice from the red-hot SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 15 of the 2021 season on an incredible 132-96 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated Chiefs vs. Chargers 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and betting lines for Chiefs vs. Chargers:

Chiefs vs. Chargers spread: Kansas City -3Chiefs vs. Chargers over-under: 52 points Chiefs vs. Chargers money line: Kansas City -160, Los Angeles +140 KC: Chiefs are 4-0 against the spread in their last four games overall LAC: Chargers are 5-1 ATS in their last six Thursday games

Featured Game | Los Angeles Chargers vs. Kansas City…

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