49ers vs. Rams how to watch: TV, live stream, odds, prediction, keys for ‘Monday Night Football’ showdown

The final game of Week 10 of the 2021 NFL season pits NFC West rivals against each other. The Los Angeles Rams, coming off a disappointing home loss to the Tennessee Titans last week, travel to Northern California to take on the San Francisco 49ers, who have lost five of their last six games after starting the season 2-0. 

This game should mark the Rams debuts for Von Miller and Odell Beckham, while it will also be their first game since losing Robert Woods for the season. L.A. has an opportunity to gain some ground on the division-leading Cardinals after Arizona lost to the Carolina Panthers on Sunday. The 49ers are pretty far back in the playoff race at the moment, but they do at least have an opportunity to play spoiler here. 

So, can the Rams get back to their winning ways, or will the Niners send them into the loss column once again? We’ll find out Monday evening. But first, let’s break down the matchup. 

How to watch

Date: Monday, Nov. 15 | Time: 8:15 p.m. ET
Location: Levi’s Stadium (Santa Clara, California)
 ESPN | Stream: fuboTV (click here)
Follow: CBS Sports App
Odds: Rams -3.5, O/U 50

When the Rams have the ball

The Rams suffered a tremendous loss in Friday’s practice, when Woods went down for the year with a torn ACL. The Beckham signing softens the blow a bit as it prevents the Rams from having to dig even deeper into their wide receiver depth chart, but Woods and Beckham are much different players. The Rams are almost surely not going to use Odell the same way they did Woods in the run game, for instance, and Woods’ facility and willingness to do the dirty work as a blocker is part of what made him such a valuable player for this offense. 

In Woods’ absence, it seems more likely that Van Jefferson will play more of Woods’ role, while Beckham slides into Jefferson’s role as a field-stretcher and back side threat. It’s a role that Beckham is well-suited for,…


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